Journal of
Parasitology and Vector Biology

  • Abbreviation: J. Parasitol. Vector Biol.
  • Language: English
  • ISSN: 2141-2510
  • DOI: 10.5897/JPVB
  • Start Year: 2009
  • Published Articles: 213

Full Length Research Paper

Seroprevalence and molecular characterization of Toxoplasma gondii among patients at the Pasteur Institute of Côte d’Ivoire

Bosson-Vanga A. H.
  • Bosson-Vanga A. H.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Essy K. J.
  • Essy K. J.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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Bonouman-Ira A. V.
  • Bonouman-Ira A. V.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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Miezan A. J. S.
  • Miezan A. J. S.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Koné F
  • Koné F
  • Center for Diagnosis and Research on AIDS and Other Infectious Diseases (CeDReS), University Hospital of Treichville, 01 BP V 03 Abidjan 01, Côte d’Ivoire.
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Kouman K. B. A.
  • Kouman K. B. A.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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Tuo K.
  • Tuo K.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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Aka T. C.
  • Aka T. C.
  • Center for Diagnosis and Research on AIDS and Other Infectious Diseases (CeDReS), University Hospital of Treichville, 01 BP V 03 Abidjan 01, Côte d’Ivoire.
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N’docho A. F. T.
  • N’docho A. F. T.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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Yapo V.
  • Yapo V.
  • Center for Diagnosis and Research on AIDS and Other Infectious Diseases (CeDReS), University Hospital of Treichville, 01 BP V 03 Abidjan 01, Côte d’Ivoire.
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Koné E. G. M.
  • Koné E. G. M.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Konaté-Touré A.
  • Konaté-Touré A.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Angora K. E.
  • Angora K. E.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Bedia-Tanoh A. V.
  • Bedia-Tanoh A. V.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Kiki-Barro P. C. M.
  • Kiki-Barro P. C. M.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Kassi K. F.
  • Kassi K. F.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Yavo W.
  • Yavo W.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Menan E. I. H.
  • Menan E. I. H.
  • Parasitology and Mycology Laboratory, Training Research Unit of Pharmaceutical and Biological Sciences, University of Félix Houphouët Boigny, BPV 34, Abidjan, Côte d’Ivoire.
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Touré O. A.
  • Touré O. A.
  • Parasitology-Mycology Laboratory, Pasteur Institute of Côte d’Ivoire, 01 BPV 490, Abidjan, Côte d’Ivoire.
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  •  Received: 21 February 2025
  •  Accepted: 28 April 2025
  •  Published: 31 May 2025

Abstract

Toxoplasmosis, a zoonosis caused by Toxoplasma gondii, represents an emerging threat to global public health. Serological tests are the primary methods for the routine diagnosis of toxoplasmosis. Tests may fail to detect specific anti-toxoplasma antibodies during the early phase of the infection and during T. gondii infection in immuno-compromised patients. This is why it is useful to combine serology with molecular detection of T. gondii. Thus, this study aimed to perform molecular detection of T. gondii on seropositive patients for toxoplasma serology at the Institute Pasteur of Côte d’Ivoire. Following serology, molecular detection with DNA extraction from whole blood and polymerase chain reaction (PCR) was performed in seropositive patients. Out of the 323 enrolled patients, 162 (50.15%) showed IgG antibodies against T. gondii; 11 of them (3.40%) had both IgG and IgM. No patients were found with exclusive IgM antibodies. No parasite DNA was detected in their blood samples. A bivariate analysis did not indicate an association between seropositivity to T. gondii and variables of interest. The prevalence of T. gondii infection suggests significant exposure to the parasite. Seroprevalence was not significantly associated with sex or age. According to this study’s knowledge, it is the first study to detect T. gondii DNA in Côte d’Ivoire, which unfortunately was not detected. T. gondii should not be underestimated because negative results indicate the absence of detectable DNA but do not exclude the presence of the organism or active or recent disease.

Key words: Toxoplasmosis, Toxoplasma gondii, seroprevalence, molecular diagnosis, Côte d’Ivoire.

Copyright © 2026 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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