Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3860

Full Length Research Paper

Malaria parasite clearance rate of crude methanol extract of Cryptolepis sanguinolenta in mice infected with chloroquine sensitive strain of Plasmodium berghei

Eze, Chinelo C.
  • Eze, Chinelo C.
  • Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
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Attama, Anthony A.
  • Attama, Anthony A.
  • Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
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Ibezim, Emmanuel C.
  • Ibezim, Emmanuel C.
  • Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
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Berebon, Dinebari P.
  • Berebon, Dinebari P.
  • Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
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Agbo, Martina C.
  • Agbo, Martina C.
  • Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
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  •  Received: 17 July 2018
  •  Accepted: 16 August 2018
  •  Published: 10 October 2018

References

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Ajayi AF, Akhigbe RE, Adewumi OM, Olaleye SB (2012). Haematological evaluation of Cryptolepis sanguinolenta stems ethanolic extract in rats. International Journal of Medicine and Biomedical Research 1(1):56-61.
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Barku VYA, Opoku-Boahen Y, Dzotsi EY (2012). Isolation and pharmacological activities of alkaloids from Cryptolepis sanguinolenta (Lindl) schlt. International Research Journal of Biochemistry and Bioinformatics 2(3): 58-61.
 

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Donkor AF (2016). Efficacy, Pharmacokinetics and safety evaluation of Cryptolepine-Artemisinin based combinations in the management of uncomplicated malaria (Doctoral dissertation).
 

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Olorunniyi OF, Morenikeji OA (2014). In vivo antimalarial activity of crude aqueous leaf extract of Pyrenacantha staudtii against Plasmodium berghei (NK65) in infected mice. African Journal of Pharmacy and Pharmacology 8(12):342-345.
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Oluyemi OF, Folayele OT (2017). Effects of some micronutrients on mice infected with Plasmodium berghei. Journal of Public Health and Epidemiology 10(1):21-27.
 

Osafo N, Mensah KB, and Yeboah OK (2017). Phytochemical and Pharmacological Review of Cryptolepis sanguinolenta (Lindl.) Schlechter. Advances in Pharmacological Sciences.
 

Osonwa UE, Majekodunmi SO, Osegbo E, Udobre A (2017). Enhancement of Antimalaria Effect of Mefloquine by Chlorpheniramine. American Journal of Medicine and Medical Sciences 7(6):248-264.
 

Parker EJ, Mary CU, Nwodo Okwesili FC, Ikechukwu UR (2016). Hematological Responses and Percentage Parastaemia in Malaria-Infected Mice Treated with Ethanol Extract of Zapoteca portoricensis Roots. Biochem Anal Biochem 5(252):2161-1009.
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Pillai P, Suresha P, Mishrab G, Annapurnaa M (2011). Evaluations of the acute and sub-acute toxicity of the methanolic leaf extract of Plectranthus amboinicus (Lour) Sprengin Balb C mice. European Journal of Experimental Biology 1:236-245
 

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Yeo SJ, Liu DX, Kim HS and Park H (2017). Anti-malarial effect of novel chloroquine derivatives as agents for the treatment of malaria. Malaria Journal 16(1):80.
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